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Idamycin and Heart disease

Result of checking the interaction of drug Idamycin and disease Heart disease for safety when used together.

Check result:

Idamycin <> Heart disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Idarubicin can cause myocardial toxicity leading to congestive heart failure. Patients with preexisting heart disease or prior anthracycline therapy are at increased risk of congestive heart failure. Close clinical monitoring of cardiac function, such as an electrocardiogram and/or determination of left ventricular ejection fraction, prior to each course of therapy is recommended.

References:

Chan-Lam D, Copplestone JA, Prentice A, Price R, Johnson S, Phillips M "Idarubicin cardiotoxicity in acute myeloid leukaemia." Lancet 340 (1992): 185-6
"Product Information. Idamycin (idarubicin)." Pharmacia and Upjohn, Kalamazoo, MI.
Villani F, Galimberti M, Comazzi R, Crippa F "Evaluation of cardiac toxicity of idarubicin (4- demethoxydaunorubicin)." Eur J Cancer Clin Oncol 25 (1989): 13-8
Bertelli G, Amoroso D, Pronzato P, Rosso R "Idarubicin: an evaluation of cardiac toxicity in 77 patients with solid tumors." Anticancer Res 8 (1988): 645-6
Gillies H, Liang R, Rogers H, Harper P, Parapia L, Cox G, Johnson S "Phase II trial of idarubicin in patients with advanced lymphoma." Cancer Chemother Pharmacol 21 (1988): 261-4

Idamycin

Generic Name: idarubicin

Brand Name: Idamycin PFS, Idamycin

Synonyms: n.a.

What is Idamycin?