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Impavido and Liver disease

Result of checking the interaction of drug Impavido and disease Liver disease for safety when used together.

Check result:

Impavido <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Elevations in liver transaminases (ALT, AST) and bilirubin were observed in clinical trials of miltefosine for the treatment of visceral leishmaniasis. Therapy with miltefosine should be administered cautiously in patients with liver disease, as the pharmacokinetics of miltefosine have not been studied in this population. Patients with serum ALT or AST levels 3 times or higher than the upper limit of normal and bilirubin levels 2 times or higher than the upper limit of normal were excluded from clinical trials. Liver transaminases and bilirubin should be monitored regularly during therapy.

Impavido

Generic Name: miltefosine

Brand Name: Impavido

Synonyms: n.a.

What is Impavido?