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Amantadine Extended-Release Capsules and Hypotension

Result of checking the interaction of drug Amantadine Extended-Release Capsules and disease Hypotension for safety when used together.

Check result:

Amantadine Extended-Release Capsules <> Hypotension

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Dopamine agonists may impair the systemic regulation of blood pressure, with resultant orthostatic hypotension, especially during dose escalation. Therapy with dopamine agonists should be monitored carefully in patients with Parkinson's disease since they may have an impaired ability to respond to an orthostatic challenge, and also in patients receiving antihypertensive drugs.

References:

"Product Information. Sinemet CR (carbidopa-levodopa)." Dupont Pharmaceuticals, Wilmington, DE.
Iwasaki S, Hamaguchi K, Iwasaki A, Takakusagi M, Narabayashi Y "Hypotensive effect of long-term levodopa in patients with Parkinson's disease." Eur Neurol 30 (1990): 194-9
Hoehn MM "Levodopa-induced postural hypotension. Treatment with fludrocortisone." Arch Neurol 32 (1975): 50-1
"Product Information. Mirapex (pramipexole)." Boehringer Ingelheim, Ridgefield, CT.
"Product Information. Dostinex (cabergoline)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Sinemet (carbidopa-levodopa)." DuPont Pharmaceuticals, Wilmington, DE.

Amantadine Extended-Release Capsules

Generic Name: amantadine

Brand Name: Gocovri, Osmolex ER, Symmetrel

Synonyms: Amantadine

What is Amantadine Extended-Release Capsules?

Another drug Delete

Amantadine Extended-Release Capsules <> Hypotension

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

Consumer:

Amantadine may occasionally cause orthostatic hypotension. Patients with hypotension should be monitored for exacerbation of their condition during therapy with amantadine. Dosage adjustments may be necessary, and patients should be advised not to rise abruptly from a sitting or recumbent position.

References: