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K-Phos No. 2 and Aluminum toxicity/renal impairment

Result of checking the interaction of drug K-Phos No. 2 and disease Aluminum toxicity/renal impairment for safety when used together.

Check result:
K-Phos No. 2 <> Aluminum toxicity/renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Potassium phosphate injections contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration in patients with renal impairment. Preterm infants are particularly at risk for aluminum toxicity because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which also contain aluminum. Patients with renal impairment, including preterm infants, who receive greater than 4 to 5 mcg/kg/day of parenteral aluminum can accumulate aluminum to levels associated with central nervous system and bone toxicity. Potassium phosphate injection for parenteral nutrition is not recommended in adults weighing less than 45 kg or pediatric patients less than 12 years of age or weighing less than 40 kg due to the risks of aluminum toxicity.

K-Phos No. 2

Generic Name: potassium phosphate / sodium phosphate

Brand Name: K-Phos MF, K-Phos Neutral, K-Phos No. 2, PHOS-NaK, Phospha 250 Neutral, Uro-KP-Neutral, Neutra-Phos, Vis-Phos N, Virt-Phos 250 Neutral, Av-Phos 250 Neutral, Phospho-Trin 250 Neutral, Phosphorous Supplement

Synonyms: K-PHOS No. 2

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