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Leustatin and Renal dysfunction

Generic Name: cladribine
Dosage Forms: injection, solution
Other Brand Names: Leustatin , Mavenclad

Result of checking the interaction of drug Leustatin and disease Renal dysfunction for safety when used together.

Check result:

Leustatin <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The effect of renal impairment on the elimination of cladribine has not been assessed in humans. Renal toxicity such as acidosis, anuria, elevated serum creatinine has been reported with doses four to nine times the recommended dosage of cladribine for hairy cell leukemia. Therapy with cladribine should be administered cautiously in patient with compromised renal function. Clinical monitoring of renal function is recommended.

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