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Lonsurf and Myelosuppression

Result of checking the interaction of drug Lonsurf and disease Myelosuppression for safety when used together.

Check result:
Lonsurf <> Myelosuppression
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of products containing the combination ingredients, trifluridine and tipiracil may cause severe myelosuppression (Grade 3-4). It is recommended to monitor for signs and symptoms suspected of myelosuppression such as anemia, neutropenia, thrombocytopenia, and febrile neutropenia. Obtain complete blood counts prior to and on Day 15 of each cycle of the combination product containing trifluridine and tipiracil and more frequently as clinically indicated. Withhold the use of the agent for severe myelosuppression and resume at the next lower dosage according to the manufacturer instructions.

Lonsurf

Generic Name: tipiracil / trifluridine

Brand Name: Lonsurf

Synonyms: n.a.

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