Drug search by name

Ammonul and Renal/liver dysfunction

Result of checking the interaction of drug Ammonul and disease Renal/liver dysfunction for safety when used together.

Check result:

Ammonul <> Renal/liver dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Phenylacetate conjugates with glutamine in the liver and kidneys to form phenylacetylglutamine, via acetylation. Phenylacetylglutamine is excreted by the kidneys via glomerular filtration and tubular secretion. Similarly, preceded by acylation, benzoate conjugates with glycine to form hippuric acid, which is rapidly excreted by the kidneys by glomerular filtration and tubular secretion. It is recommended to use caution and close monitoring when using products containing sodium phenylacetate and sodium benzoate in patients with impaired renal function and in patients with hepatic insufficiency.

Ammonul

Generic Name: sodium benzoate / sodium phenylacetate

Brand Name: Ammonul

Synonyms: n.a.

What is Ammonul?