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Mekinist and Hemorrhage

Result of checking the interaction of drug Mekinist and disease Hemorrhage for safety when used together.

Check result:

Mekinist <> Hemorrhage

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of trametinib may increase the incidence of hemorrhagic events, including major hemorrhages defined as symptomatic bleeding in a critical area or organ. It is recommended to discontinue the use of trametinib for all Grade 4 hemorrhagic events and temporarily withhold the use of trametinib for Grade 3 hemorrhagic events, if improved, resume the dose at the next lower dose level. Close monitoring is recommended. Care should be taken when using this agent in patients at risk.

Mekinist

Generic Name: trametinib

Brand Name: Mekinist

Synonyms: n.a.

What is Mekinist?