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Mekinist and Hepatic impairment

Result of checking the interaction of drug Mekinist and disease Hepatic impairment for safety when used together.

Check result:

Mekinist <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Based on a population pharmacokinetic analysis of trametinib, no dose adjustment is recommended in patients with mild hepatic impairment. There are no data on the pharmacokinetics of trametinib in patients with moderate or severe hepatic impairment. Close monitoring is recommended for these patients.

Mekinist

Generic Name: trametinib

Brand Name: Mekinist

Synonyms: n.a.

What is Mekinist?