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Methoxsalen Soft-Gelatin Capsules and Skin cancer

Result of checking the interaction of drug Methoxsalen Soft-Gelatin Capsules and disease Skin cancer for safety when used together.

Check result:
Methoxsalen Soft-Gelatin Capsules <> Skin cancer
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of methoxsalen (a psoralen) with ultraviolet radiation (UVA) is contraindicated in patients with melanoma, invasive squamous cell carcinomas, or a history of melanoma. PUVA (psoralen and UVA photochemotherapy) may be associated with increased risks of squamous cell carcinoma, basal cell carcinoma and melanoma. Methoxsalen markedly enhances skin reactivity to UVA, and exposure to sunlight and/or UVA can cause premature aging of the skin and skin cancer. If necessary, patients with a current or past history of multiple basal cell carcinomas or other nonmelanoma skin cancers may be treated with PUVA but should be carefully monitored. The usual restrictions concerning sun exposure before and after treatment as well as prescribed dosage must be followed closely.

References:
  • "Product Information. Oxsoralen Lotion (methoxsalen topical)." ICN Pharmaceuticals, Costa Mesa, CA.
  • "Product Information. Oxsoralen (methoxsalen)." ICN Pharmaceuticals Inc, Costa Mesa, CA.
Methoxsalen Soft-Gelatin Capsules

Generic Name: methoxsalen

Brand Name: 8-Mop, Oxsoralen-Ultra, Uvadex

Synonyms: Methoxsalen, Methoxsalen (Systemic)

Interaction with food and lifestyle