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Mycophenolate Mofetil Injection and HGPRT deficiency

Result of checking the interaction of drug Mycophenolate Mofetil Injection and disease HGPRT deficiency for safety when used together.

Check result:

Mycophenolate Mofetil Injection <> HGPRT deficiency

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Mycophenolate mofetil is an inosine monophosphate dehydrogenase (IMPDH) inhibitor; therefore it should be avoided in patients with hereditary deficiencies of hypoxanthine-guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan and Kelley-Seegmiller syndromes because it may cause an exacerbation of disease symptoms characterized by the overproduction and accumulation of uric acid leading to symptoms associated with gout such as acute arthritis, tophi, nephrolithiasis or urolithiasis and renal disease including renal failure.

Mycophenolate Mofetil Injection

Generic Name: mycophenolate mofetil

Brand Name: Cellcept, Myfortic, MMF

Synonyms: Mycophenolate, Mycophenolate mofetil (oral/injection)

What is Mycophenolate Mofetil Injection?