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Mycophenolate Tablets and GI hemorrhage

Result of checking the interaction of drug Mycophenolate Tablets and disease GI hemorrhage for safety when used together.

Check result:

Mycophenolate Tablets <> GI hemorrhage

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Gastrointestinal, rectal, and duodenal hemorrhage, hemorrhagic pancreatitis and rarely, large-intestine perforation have occurred in patients receiving mycophenolate. These events occurred primarily at dosages of mycophenolate >2 grams per day. Therapy with mycophenolate should be administered cautiously in patients with active gastrointestinal disease.

References:

"Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Taylor DO, Ensley RD, Olsen SL, Dunn D, Renlund DG "Mycophenolate mofetil (RS-61443): preclinical, clinical, and three- year experience in heart transplantation." J Heart Lung Transplant 13 (1994): 571-82
Kirklin JK, Bourge RC, Naftel DC, Morrow WR, Deierhoi MH, Kauffman RS, White-Williams C, Nomberg RI, Holman WL, Smith DC Jr "Treatment of recurrent heart rejection with mycophenolate mofetil (RS- 61443): initial clinical experience." J Heart Lung Transplant 13 (1994): 444-50
"Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. European Mycophenolate Mofetil Cooperative Study Group." Lancet 345 (1995): 1321-5
Deierhoi MH, Kauffman RS, Hudson SL, Barber WH, Curtis JJ, Julian BA, Gaston RS, Laskow DA, Diethelm AG "Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single center." Ann Surg 217 (1993): 476-82;disc. 482-4

Mycophenolate Tablets

Generic Name: mycophenolate mofetil

Brand Name: Cellcept, Myfortic, MMF

Synonyms: Mycophenolate mofetil (oral/injection), Mycophenolate

What is Mycophenolate Tablets?