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Navelbine and Hepatic dysfunction

Generic Name: vinorelbine
Dosage Forms: injection
Other Brand Names: Navelbine

Result of checking the interaction of drug Navelbine and disease Hepatic dysfunction for safety when used together.

Check result:

Navelbine <> Hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Vinorelbine is extensively metabolized by the liver. The pharmacokinetic disposition of vinorelbine in patients with hepatic impairment has not been assessed. Therapy with vinorelbine should be administered cautiously and the dosage reduced in patients with compromised hepatic function.

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