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Orfadin and Leukopenia/thrombocytopenia

Result of checking the interaction of drug Orfadin and disease Leukopenia/thrombocytopenia for safety when used together.

Check result:

Orfadin <> Leukopenia/thrombocytopenia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

In clinical trials, patients treated with oral formulations of nitisinone and dietary restriction developed transient leukopenia (3%), thrombocytopenia (3%), or both (1.5%). No patients developed infections or bleeding as a result of the episodes of leukopenia and thrombocytopenia. Caution is advised especially in patients with low blood cell counts. Platelet and white blood cell counts should be monitored during therapy with nitisinone.

Orfadin

Generic Name: nitisinone

Brand Name: Orfadin, Nityr

Synonyms: n.a.

What is Orfadin?