Drug search by name

Pentam 300 and Asthma/COPD

Result of checking the interaction of drug Pentam 300 and disease Asthma/COPD for safety when used together.

Check result:

Pentam 300 <> Asthma/COPD

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Orally inhaled pentamidine may induce bronchospasm and cough. Therapy with aerosolized pentamidine should be administered cautiously in patients with severe bronchospastic disease or a history of extensive smoking. Pretreatment with a beta-2 adrenergic bronchodilator prior to each dose of aerosolized pentamidine may be helpful in patients who experience respiratory symptoms from the medication.

References:

Leigh TR, Wiggins J, Gazzard BG, Collins JV "Effect of terbutaline on bronchoconstriction induced by nebulised pentamidine." Thorax 46 (1991): 122-3
Quieffin J, Hunter J, Schechter MT, et al "Aerosol pentamidine-induced bronchoconstriction." Chest 100 (1991): 624-7
"Product Information. NebuPent (pentamidine)." Fujisawa, Deerfield, IL.
Ong EL, Hanley SP, Mandal BK "Bronchoconstriction, nebulised pantamidine, and mast cells." Lancet 04/29/89 (1989): 956
Chan CK, Hyland RH, Yu D-G, et al "Acute pulmonary effects of aerosolized pentamidine: a randomized controlled study." Chest 98 (1990): 907-10
Katzman M, Meade W, Iglar K, et al "High incidence of bronchospasm with regular administration of aerosolised pentamidine." Chest 101 (1992): 79-81

Pentam 300

Generic Name: pentamidine

Brand Name: Nebupent, Pentam 300, Pentam

Synonyms: n.a.

What is Pentam 300?