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Perphenazine and amitriptyline and Dementia

Result of checking the interaction of drug Perphenazine and amitriptyline and disease Dementia for safety when used together.

Check result:
Perphenazine and amitriptyline <> Dementia
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Elderly patients with dementia- related psychosis treated with antipsychotic drugs are at an increased risk of death, mostly from cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) causes. A causal relationship with antipsychotic use has not been established. In controlled trials, treatment with some atypical antipsychotic drugs was also associated with an increased risk of cerebrovascular adverse events (e.g., stroke, transient ischemic attack), including fatalities, in elderly patients with dementia- related psychosis. These agents are not approved for the treatment of patients with dementia- related psychosis.

Perphenazine and amitriptyline

Generic Name: amitriptyline / perphenazine

Brand Name: Etrafon Forte, Triavil, Etrafon 2-10, Etrafon 2-25

Synonyms: Amitriptyline and perphenazine, Amitriptyline and Perphenazine

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