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Aranesp (Darbepoetin Alfa Prefilled Syringes) and Seizures

Result of checking the interaction of drug Aranesp (Darbepoetin Alfa Prefilled Syringes) and disease Seizures for safety when used together.

Check result:

Aranesp (Darbepoetin Alfa Prefilled Syringes) <> Seizures

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of erythropoiesis stimulating agents increases the risk of seizures in patients with chronic renal failure. Seizure development may be related to the rate of rise in hematocrit, which is also associated with blood pressure elevations. It is recommended to monitor patients closely for the development of premonitory neurologic symptoms during the first several months after the administration of these agents. Patients with epilepsy or predisposed to seizures should be monitored closely for blood pressure changes and neurologic symptoms during therapy with these agents.

References:

"Product Information. Epogen (epoetin alfa)." Amgen, Thousand Oaks, CA.
Bennett WM "Side effects of erythropoietin therapy." Am J Kidney Dis 18 (1991): 84-6
Singbartl G "Adverse events of erythropoietin in long-term and in acute short-term treatment." Clin Investig 72 (1994): s36-43
Temple RM, Eadington DW, Swainson CP, Winney R "Seizure related to erythropoietin treatment in patients undergoing dialysis." BMJ 300 (1990): 46
Beccari M "Seizures in dialysis patients treated with recombinant erythropoietin - review of the literature and guidelines for prevention." Int J Artif Organs 17 (1994): 5-13
"Product Information. Procrit (epoetin alfa)." Ortho Biotech Inc, Raritan, NJ.

Aranesp (Darbepoetin Alfa Prefilled Syringes)

Generic Name: darbepoetin alfa

Brand Name: Aranesp, Aranesp SureClick, Aranesp Albumin Free, Aranesp SingleJect

Synonyms: Aranesp

What is Aranesp (Darbepoetin Alfa Prefilled Syringes)?