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Promethazine VC with Codeine and BPH

Result of checking the interaction of drug Promethazine VC with Codeine and disease BPH for safety when used together.

Check result:

Promethazine VC with Codeine <> BPH

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sympathomimetic agents may cause or worsen urinary difficulty in patients with prostate enlargement due to smooth muscle contraction in the bladder neck via stimulation of alpha-1 adrenergic receptors. Therapy with sympathomimetic agents should be administered cautiously in patients with hypertrophy or neoplasm of the prostate.

References:

Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 (1990): 47-50
"Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.
Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):

Promethazine VC with Codeine

Generic Name: codeine / phenylephrine / promethazine

Brand Name: Promethazine VC with Codeine, Phenergan VC with Codeine, M-Phen

Synonyms: n.a.

What is Promethazine VC with Codeine?