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Retrovir (Zidovudine Injection) and Renal dysfunction

Result of checking the interaction of drug Retrovir (Zidovudine Injection) and disease Renal dysfunction for safety when used together.

Check result:

Retrovir (Zidovudine Injection) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with clinically significant renal impairment may be at greater risk for toxicities and adverse effects from nucleoside reverse transcriptase inhibitors (NRTIs) due to decreased drug clearance. Dosage adjustments are recommended. In addition, these patients should be monitored closely during NRTI therapy, and dosages adjusted further if necessary.

References:

"Product Information. HIVID (zalcitabine)." Roche Laboratories, Nutley, NJ.
"Product Information. Retrovir (zidovudine)." Glaxo Wellcome, Research Triangle Park, NC.
"Product Information. Zerit (stavudine)." Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Epivir (lamivudine)." Glaxo Wellcome, Research Triangle Park, NC.

Retrovir (Zidovudine Injection)

Generic Name: zidovudine

Brand Name: Retrovir

Synonyms: Retrovir (oral/injection), Retrovir

What is Retrovir (Zidovudine Injection)?