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Riluzole and Renal dysfunction

Generic Name: riluzole
Dosage Forms: n.a.
Other Brand Names: Rilutek , Tiglutik

Result of checking the interaction of drug Riluzole and disease Renal dysfunction for safety when used together.

Check result:

Riluzole <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Riluzole and its metabolites are eliminated via the kidney. Therapy with riluzole should be administered cautiously in patients with renal dysfunction. Reduced clearance and higher plasma levels may occur in these patients. Women, native Japanese patients, and the elderly may metabolize or excrete riluzole at a slower rate. The need for dosage adjustment is not known.

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