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Singulair (Montelukast Oral Granules) and Liver disorder

Result of checking the interaction of drug Singulair (Montelukast Oral Granules) and disease Liver disorder for safety when used together.

Check result:

Singulair (Montelukast Oral Granules) <> Liver disorder

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Reports of cholestatic hepatitis, hepatocellular liver-injury, and mixed-pattern liver injury have been reported in patients treated with montelukast sodium that had underlying potential for liver disease, such as alcohol use or other forms of hepatitis. Patients with mild-to-moderate hepatic insufficiency and clinical evidence of cirrhosis had evidence of decreased metabolism of montelukast. No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency. The pharmacokinetics of montelukast sodium in patients with more severe hepatic impairment or with hepatitis have not been evaluated. Use caution when prescribing montelukast to these patients.

Singulair (Montelukast Oral Granules)

Generic Name: montelukast

Brand Name: Singulair

Synonyms: Singulair

What is Singulair (Montelukast Oral Granules)?