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Sinus Nasal Spray and BPH

Result of checking the interaction of drug Sinus Nasal Spray and disease BPH for safety when used together.

Check result:
Sinus Nasal Spray <> BPH
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Topically applied sympathomimetic agents are systemically absorbed, with the potential for producing clinically significant systemic effects, particularly during prolonged or indiscriminate use. In patients with prostate enlargement, urinary difficulty may develop or worsen due to smooth muscle contraction in the bladder neck via stimulation of alpha-1 adrenergic receptors. Therapy with topical sympathomimetic agents should be administered cautiously in patients with hypertrophy or neoplasm of the prostate. It is important that the recommended dosages of the individual products not be exceeded.

References:
  • "Product Information. Collyrium Fresh (tetrahydrozoline)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • "Product Information. Naphcon (naphazoline ophthalmic)" Alcon Laboratories Inc, Fort Worth, TX.
  • "Product Information. Afrin (oxymetazoline nasal)" Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Neo-Synephrine Nasal (phenylephrine nasal)" Southwood Pharmaceuticals Inc, Irvine, CA.
  • "Product Information. Pretz-D (ephedrine nasal)" Parnell Pharmaceuticals Inc, San Rafael, CA.
  • "Product Information. Otriviv (xylometazoline nasal)" Novartis Pharmaceuticals, East Hanover, NJ.
  • "Product Information. Ocuclear (oxymetazoline ophthalmic)" Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Tyzine (tetrahydrozoline)." Kenwood Laboratories, Fairfield, NJ.
  • "Product Information. Vicks Vapor Inhaler (desoxyephedrine nasal)" Procter and Gamble Pharmaceuticals, Cincinnati, OH.
  • "Product Information. Benzedrex (propylhexedrine nasal)" Menley and James Laboratories Inc, Horsham, PA.
  • "Product Information. Neo-Synephrine (phenylephrine ophthalmic)" Sanofi Winthrop Pharmaceuticals, New York, NY.
  • Ellis PP "Systemic reactions to topical therapy." Int Ophthalmol Clin 11 (1971): 1-11
  • "Product Information. Privine (naphazoline nasal)" Novartis Consumer Health, Summit, NJ.
  • Lansche RK "Systemic reactions to topical epinephrine and phenylephrine." Am J Ophthalmol 61 (1966): 95-8
Sinus Nasal Spray

Generic Name: oxymetazoline nasal

Brand Name: 12 Hour Nasal, Afrin, Afrin No Drip Sinus, Allerest 12 Hour Nasal Spray, Dristan 12-Hour, Duramist Plus, Duration, Mucinex Full Force, Mucinex Moisture Smart, Nasal Mist, Neo-Synephrine 12 Hour, Nostrilla, NRS Nasal, Sinarest Nasal, Sinex Long-Acting, Sudafed OM Sinus Cold, Zicam Extreme Congestion Relief, Zicam Sinus Relief, Afrin Menthol Spray, Afrin Nasal Spray, Afrin NoDrip Extra Moisture, Afrin NoDrip Original, Afrin NoDrip Sinus, Afrin Sinus, Dristan Spray, Long Lasting Nasal Spray, Mucinex Nasal Spray Full Force, Mucinex Nasal Spray Moisture, Mucinex Sinus-Max Clear & Cool, Nasal Decongestant Spray, Nasal Spray 12 Hour, Nasal Spray Max Strength, Neo-Synephrine 12 Hour Spray, NRS Nasal Relief, QlearQuil, Sinus Nasal Spray, Vicks Sinex 12 Hour Decongest, Vicks Sinex Moisturizing, Vicks Sinex Severe Decongest, Vicks Sinex

Synonyms: Oxymetazoline nasal, Oxymetazoline (Nasal)

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