Drug search by name

Sivextro (Tedizolid Injection) and Neutropenia

Result of checking the interaction of drug Sivextro (Tedizolid Injection) and disease Neutropenia for safety when used together.

Check result:

Sivextro (Tedizolid Injection) <> Neutropenia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The antibacterial activity of tedizolid may be reduced in the absence of granulocytes. In the mouse thigh infection model of Staphylococcus aureus, bacterial stasis was achieved in non-granulocytopenic mice at a human-equivalent dose of approximately 100 mg/day, whereas a human-equivalent dose of approximately 2000 mg/day was required in granulocytopenic mice with neutrophil count less than 100 cells/mL. The safety and efficacy of tedizolid in patients with neutropenia (neutrophil counts <1000 cells/mm3) have not been adequately evaluated. Alternative antibiotics should be considered in neutropenic patients who require treatment for acute bacterial skin and skin structure infections.

Sivextro (Tedizolid Injection)

Generic Name: tedizolid

Brand Name: Sivextro

Synonyms: Sivextro

What is Sivextro (Tedizolid Injection)?