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Sofosbuvir, velpatasvir, and voxilaprevir and Hepatic impairment

Result of checking the interaction of drug Sofosbuvir, velpatasvir, and voxilaprevir and disease Hepatic impairment for safety when used together.

Check result:
Sofosbuvir, velpatasvir, and voxilaprevir <> Hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sofosbuvir is extensively metabolized in the liver. The safety and efficacy of sofosbuvir as a single agent have not been established in patients with decompensated cirrhosis. No dosage adjustment is required for patients with mild, moderate or severe hepatic impairment (Child-Pugh Class A, B or C).

Sofosbuvir, velpatasvir, and voxilaprevir

Generic Name: sofosbuvir / velpatasvir / voxilaprevir

Brand Name: Vosevi

Synonyms: Sofosbuvir, Velpatasvir, and Voxilaprevir

Sofosbuvir, velpatasvir, and voxilaprevir <> Hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of voxilaprevir is not recommended in patients with moderate or severe hepatic impairment (Child-Pugh B or C) or those with any history of prior hepatic decompensation due to higher exposures of the drug in these patients.

Sofosbuvir, velpatasvir, and voxilaprevir

Generic Name: sofosbuvir / velpatasvir / voxilaprevir

Brand Name: Vosevi

Synonyms: Sofosbuvir, Velpatasvir, and Voxilaprevir

Interaction with food and lifestyle