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Streptozocin and Hepatic dysfunction

Generic Name: streptozocin
Dosage Forms: n.a.
Other Brand Names: Zanosar

Result of checking the interaction of drug Streptozocin and disease Hepatic dysfunction for safety when used together.

Check result:

Streptozocin <> Hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Unspecified hepatic dysfunction has been noted during streptozocin therapy. The pharmacokinetic disposition of streptozocin has not been extensively studied. Therapy with streptozocin should be administered cautiously in patients with a history or predisposition to compromised hepatic function. Liver function tests should be done at least weekly and dosage adjustments or discontinuance of therapy may be indicated, depending upon the degree of toxicity noted.

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