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Succinylcholine and Malignant hyperthermia

Result of checking the interaction of drug Succinylcholine and disease Malignant hyperthermia for safety when used together.

Check result:
Succinylcholine <> Malignant hyperthermia
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of succinylcholine is contraindicated in patients with a personal or family history of malignant hyperthermia. Succinylcholine administration has been associated with acute onset of malignant hyperthermia, especially during the concomitant use of volatile anesthetics. If malignant hyperthermia occurs, anesthesia should be discontinued and supportive measures rendered promptly, including rapid cooling, inhalation of 100% oxygen, control of acidosis, support of circulation, and assurance of adequate urinary output. In addition, intravenous dantrolene sodium is recommended.

References:
  • "Product Information. Anectine (succinylcholine)." Glaxo Wellcome, Research Triangle Park, NC.
Succinylcholine

Generic Name: succinylcholine

Brand Name: Anectine, Quelicin

Synonyms: n.a.

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