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Atovaquone Suspension and Gastrointestinal absorption

Result of checking the interaction of drug Atovaquone Suspension and disease Gastrointestinal absorption for safety when used together.

Check result:

Atovaquone Suspension <> Gastrointestinal absorption

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Oral bioavailability of atovaquone is limited under fasting conditions, but is increased approximately two-fold when administered with food. Patients with gastrointestinal disorders or eating difficulties may be more likely to have impaired absorption and, consequently, subtherapeutic levels of the drug. Alternative parenteral treatment should be considered for patients unable to achieve adequate plasma concentrations of atovaquone with oral administration.

References:

Rolan PE, Mercer AJ, Weatherley BC, Holdich T, Ridout G, Meire H "Investigation of the factors responsible for a food-induced increase in absorption of a novel antiprotozoal drug 566C80." Br J Clin Pharmacol 33 (1992): p534-5
"Product Information. Mepron (atovaquone)." Glaxo Wellcome, Research Triangle Park, NC.

Atovaquone Suspension

Generic Name: atovaquone

Brand Name: Mepron

Synonyms: Atovaquone

What is Atovaquone Suspension?