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Sumaxin TS (Sulfur and Sulfacetamide Emulsion and Lotion) and Crystalluria

Result of checking the interaction of drug Sumaxin TS (Sulfur and Sulfacetamide Emulsion and Lotion) and disease Crystalluria for safety when used together.

Check result:

Sumaxin TS (Sulfur and Sulfacetamide Emulsion and Lotion) <> Crystalluria

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sulfonamides may be systemically absorbed when applied to the skin, eye, or mucosal membranes. The use of sulfonamides has been associated with crystalluria due to precipitation of the sulfonamide and/or its N4-acetyl metabolite in the urinary tract. Renal toxicity such as uro- and nephrolithiasis, nephritis, toxic nephrosis, hematuria, proteinuria, and elevated BUN and creatinine has been reported. Hydration and adequate urinary output (> 1.5 L/day) should be maintained during sulfonamide administration. Patients who are dehydrated (e.g., due to severe diarrhea or vomiting) may be at increased risk for the development of crystalluria and lithiasis and should be encouraged to consume additional amounts of liquid. Renal function tests and urinalysis should be performed regularly during prolonged therapy (> 2 weeks).

References:

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Hein R, Brunkhorst R, Thon WF, Schedel I, Schmidt RE "Symptomatic sulfadiazine crystalluria in AIDS patients: a report of two cases." Clin Nephrol 39 (1993): 254-6
"Product Information. Sulfacet-R (sulfacetamide sodium topical)" Dermik Laboratories, Collegeville, PA.
"Product Information. Azopt (brinzolamide ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
Simon D, Brosius F, Rothstein D "Sulfadiazine crystalluria revisited." Arch Intern Med 150 (1990): 2379-84
"Product Information. Trusopt (dorzolamide ophthalmic)." Merck & Co, Inc, West Point, PA.
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"Product Information. AVC Cream (sulfanilamide topical)" Aventis Pharmaceuticals, Swiftwater, PA.
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"Product Information. Klaron (sulfacetamide sodium topical)." Dermik Laboratories, Collegeville, PA.
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"Product Information. Sultrin (triple sulfa topical)" Janssen Pharmaceuticals, Titusville, NJ.
"Product Information. Sulamyd Ophthalmic Solution (sodium sulfacetamide ophthalmic)." Schering Corporation, Kenilworth, NJ.
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"Product Information. Gantrisin (sulfisoxazole ophthalmic)." Roche Laboratories, Nutley, NJ.

Sumaxin TS (Sulfur and Sulfacetamide Emulsion and Lotion)

Generic Name: sulfacetamide sodium / sulfur topical

Brand Name: Plexion TS, Sumaxin TS, Avar, BP 10-Wash, Clarifoam EF, Garimide, Plexion, Prascion Cleanser, Rosanil Cleanser, Rosula, Sulfacleans 8/4, Sumadan, Sumaxin, Suphera, Virti-Sulf, Zencia Wash, Avar LS, SSS 10-4, SSS 10-5, Avar LS Cleanser, Plexion Cleansing Cloths, Plexion SCT, Rosac, Novacet, Sulfacet-R, Zetacet, Plexion Cleanser, Rosula Cleanser, Nicosyn, Avar Cleanser, Clenia Foaming Wash, Clenia Emollient Cream, Avar Gel, Avar Green, Avar-E Emollient, Avar-E Green, Rosaderm Cleanser, Zetacet Wash, Sulfatol, Sulfatol Cleanser, Prascion FC Cloths, Prascion RA, Rosula Clarifying Wash, Prascion, Rosac Wash, Topisulf, Sulfatol C, SulZee Wash, Sulfatol SS, Sumaxin Wash, Avar-e LS, SE 10-5 SS, Avar-E, Sumadan Wash, Sumaxin CP, Sumadan XLT, Rosula Wash

Synonyms: Sumaxin TS Lotion

What is Sumaxin TS (Sulfur and Sulfacetamide Emulsion and Lotion)?