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Theracaps Cough/Cold Reliever and Cardiovascular

Result of checking the interaction of drug Theracaps Cough/Cold Reliever and disease Cardiovascular for safety when used together.

Check result:
Theracaps Cough/Cold Reliever <> Cardiovascular
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Antihistamines may infrequently cause cardiovascular adverse effects related to their anticholinergic and local anesthetic (quinidine-like) activities. Tachycardia, palpitation, ECG changes, arrhythmias, hypotension, and hypertension have been reported. Although these effects are uncommon and usually limited to overdosage situations, the manufacturers and some clinicians recommend that therapy with antihistamines be administered cautiously in patients with cardiovascular disease, hypertension, and/or hyperthyroidism.

References:
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  • "Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
  • "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
  • "Product Information. Tavist (clemastine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • "Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
  • Smith SJ "Cardiovascular toxicity of antihistamines." Otolaryngol Head Neck Surg 111 Suppl (1994): 348-54
  • "Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.
  • "Product Information. Drixoral (dextromethorphan)." Schering-Plough, Liberty Corner, NJ.
  • Schuller DE, Turkewitz D "Adverse effects of antihistamines." Postgrad Med 79 (1986): 75-86
  • Woosley RL "Cardiac actions of antihistamines." Annu Rev Pharmacol Toxicol 36 (1996): 233-52
  • "Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
  • "Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
  • "Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.
Theracaps Cough/Cold Reliever

Generic Name: acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine

Brand Name: Alka-Seltzer Plus-D Sinus/Cold, Cold Symptoms Relief Maximum Strength, EQ Cold Relief Complete, EQ Cold/Cough Plus, EQL Pain Relief/Cold, Tylenol Cold and Flu Powder, Theraflu Flu, Cold and Cough Powder, Theraflu Nightime Maximum Strength, Comtrex Day and Night, Theraflu Night Cough and Cold and Flu, Co-Apap, Vicks Formula 44M, Cough Formula M Multi-Symptom, Mapap Cold, Child Tylenol Cold Multi-Symptom Plus Cough, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Robitussin Honey Flu Nighttime, Children's Tylenol Flu, Alka-Seltzer Plus Cough and Cold Liquigel, Tylenol Cold Complete Formula, Children's Tylenol Cold Plus Cough, Contac Cold and Flu Maximum Strength, Triaminic Flu, Cough & Fever, Theraflu Cold & Cough, Theraflu Severe Cold & Congestion, Theraflu Flu & Cough, Tylenol Cold Day/Night Convenience Pack, Children’s Non-Aspirin Cold/Cough, EQL Pain Relief Plus Cold/Cough, Tylenol Children’s Cold/Cough

Synonyms: n.a.

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