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Ticarcillin and clavulanate Intravenous and Sodium/potassium

Result of checking the interaction of drug Ticarcillin and clavulanate Intravenous and disease Sodium/potassium for safety when used together.

Check result:

Ticarcillin and clavulanate Intravenous <> Sodium/potassium

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Parenteral ticarcillin disodium contains approximately 120 to 150 mg (5.2 to 6.5 mEq) of sodium per each gram of ticarcillin activity. The combination, ticarcillin-clavulanate, contains approximately 109 mg (4.75 mEq) of sodium per gram of total drug. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with ticarcillin and other extended-spectrum penicillin antibiotics, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.

References:

"Product Information. Ticar (ticarcillin)." SmithKline Beecham, Philadelphia, PA.
Nanji AA, Lindsay J "Ticarcillin associated hypokalemia." Clin Biochem 15 (1982): 118-9
Welter J, Wittman DH, Freitag V "Ticarcillin therapy of risk patients with infections due to pseudomonas aeruginosa." J Int Med Res 9 (1981): 44-51
Finch RA "Hypernatremia during lithium and ticarcillin therapy." South Med J 74 (1981): 376-7

Ticarcillin and clavulanate Intravenous

Generic Name: clavulanate / ticarcillin

Brand Name: Timentin

Synonyms: Ticarcillin and Clavulanate Potassium

What is Ticarcillin and clavulanate Intravenous?