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Trabectedin and Rhabdomyolysis

Result of checking the interaction of drug Trabectedin and disease Rhabdomyolysis for safety when used together.

Check result:

Trabectedin <> Rhabdomyolysis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rhabdomyolysis and musculoskeletal toxicity can occur with the use of trabectedin. It is recommended to obtain baseline serum creatine phosphokinase (CPK) and creatinine levels prior to initiating therapy with trabectedin and periodically during treatment as clinically indicated. Withhold trabectedin for serum CPK levels more than 2.5 times the upper limit of normal. If CPK is elevated, evaluate for signs and symptoms of rhabdomyolysis or other causes. Permanently discontinue treatment for rhabdomyolysis. Care should be taken when using this agent in patients at risk for rhabdomyolysis.

Trabectedin

Generic Name: trabectedin

Brand Name: Yondelis

Synonyms: n.a.

What is Trabectedin?