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Trametinib and Renal impairment
Result of checking the interaction of drug Trametinib and disease Renal impairment for safety when used together.
Check result:
Trametinib <> Renal impairment
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Based on a population pharmacokinetic analysis of trametinib, no dose adjustment is recommended in patients with mild or moderate renal impairment. There are no data on the pharmacokinetics of trametinib in patients with severe renal impairment. Close monitoring is recommended for these patients.
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