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Trecator and Peripheral neuropathy

Result of checking the interaction of drug Trecator and disease Peripheral neuropathy for safety when used together.

Check result:
Trecator <> Peripheral neuropathy
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Peripheral neuropathy has been associated with the use of ethionamide, but much less frequently than with isoniazid, a structurally related agent. Therapy with ethionamide should be administered cautiously in patients with preexisting peripheral neuropathy or risk factors for developing the condition, such as malnutrition, diabetes, and alcoholism. Pyridoxine (vitamin B6) at a dosage of 25 to 50 mg/day has been recommended to prevent or attenuate isoniazid-related peripheral neuropathy and may be considered for patients receiving ethionamide.

References:
  • "Product Information. Trecator-SC (ethionamide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Trecator

Generic Name: ethionamide

Brand Name: Trecator, Trecator-SC

Synonyms: n.a.

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