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Axicabtagene ciloleucel and Neurological toxicities

Result of checking the interaction of drug Axicabtagene ciloleucel and disease Neurological toxicities for safety when used together.

Check result:

Axicabtagene ciloleucel <> Neurological toxicities

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Neurologic toxicities, that were fatal or life-threatening, occurred following treatment with drugs directed against B cells, such as axicabtagene ciloleucel, and tisagenlecleucel which may be concurrent with Cytokine Release Syndrome (CRS) or after CRS resolution. Care should be exercised when using these agents in patients with neurologic disorders. It is recommended to monitor patients for signs and symptoms of neurologic toxicities after infusion and provide supportive care and/or corticosteroids as needed.

Axicabtagene ciloleucel

Generic Name: axicabtagene ciloleucel

Brand Name: Yescarta

Synonyms: Axicabtagene Ciloleucel

What is Axicabtagene ciloleucel?