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Azedra Injection and Renal toxicity

Result of checking the interaction of drug Azedra Injection and disease Renal toxicity for safety when used together.

Check result:
Azedra Injection <> Renal toxicity
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Renal failure or acute kidney injury and a demonstrated clinically significant decrease in glomerular filtration rate (GFR) has been reported in some patients receiving iobenguane I-131. Monitor renal function during and after treatment with iobenguane I-131. Patients with baseline renal impairment may be at greater risk of toxicity, and their radiation dose may be increased due to the delayed elimination of the drug. Adjust the therapeutic dose based on radiation exposure estimates from the dosimetry assessment. Perform more frequent assessments of renal function in patients with mild or moderate impairment. Iobenguane I-131 has not been studied in patients with severe renal impairment (creatinine clearance <30 mL/min), or end-stage renal disease.

Azedra Injection

Generic Name: iobenguane I 131

Brand Name: Azedra, AdreView

Synonyms: Azedra

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