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Vitamin B12 Injection and Renal impairment

Result of checking the interaction of drug Vitamin B12 Injection and disease Renal impairment for safety when used together.

Check result:
Vitamin B12 Injection <> Renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cyanocobalamin products contain aluminum that may be toxic and may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and other solutions which also contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum greater than 4-5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Caution and monitoring are recommended.

Vitamin B12 Injection

Generic Name: cyanocobalamin

Brand Name: Cobolin-M, Depo-Cobolin, Vitamin B12, B-12 Dots, Nascobal, Cobal 1000, Vitamin B-12

Synonyms: Cyanocobalamin

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