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YF-Vax and Immunodeficiency

Generic Name: yellow fever vaccine
Dosage Forms: injection
Other Brand Names: Stamaril , YF-Vax

Result of checking the interaction of drug YF-Vax and disease Immunodeficiency for safety when used together.

Check result:

YF-Vax <> Immunodeficiency

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

In general, the use of yellow fever vaccine is contraindicated in patients with primary or acquired immunodeficiency. Since yellow fever vaccine contains live attenuated virus, the absence of immune competence may potentiate the replication of vaccine virus, increase adverse host reactions, and compromise serum antibody response. In patients with severe immunosuppression or known HIV infection, the use of yellow fever vaccine may pose a theoretical risk of encephalitis. Asymptomatic HIV-infected patients may be vaccinated if potential exposure to yellow fever virus is deemed unavoidable. However, they should be monitored for adverse effects, and it may be necessary to have neutralizing antibody titers obtained before departure to gauge the adequacy of the serum antibody response. Finally, the vaccine should not be administered to anyone with a family history of congenital or hereditary immunodeficiency until the individual's immune status can be assessed and is determined to be adequate.

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