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Bacillus of calmette and guerin vaccine, live Intravesical and Infections

Result of checking the interaction of drug Bacillus of calmette and guerin vaccine, live Intravesical and disease Infections for safety when used together.

Check result:
Bacillus of calmette and guerin vaccine, live Intravesical <> Infections
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of BCG vaccine is contraindicated in patients with fever unless the cause has been determined and evaluated. If the fever is due to an infection, administration of BCG vaccine should be deferred until the patient is afebrile and done with antimicrobial therapy. When BCG vaccine is used for immunization against tuberculosis, the presence of existing infection, especially if moderate or severe, may increase the risk of an adverse host reaction and/or vaccine failure. BCG vaccine is not for the treatment of active tuberculosis. When administered intravesically for the treatment of bladder cancer, concomitant antimicrobial therapy can interfere with the effectiveness of the vaccine. Antimicrobial therapy should be evaluated to assess the effects on BCG activity. Finally, since BCG vaccine contains live bacteria, it can potentially cause a systemic BCG infection, particularly in acutely ill patients. Disseminated BCG infection has been fatal in some cases.

References:
  • "Product Information. Tice BCG Vaccine (BCG vaccine)." Organon, West Orange, NJ.
Bacillus of calmette and guerin vaccine, live Intravesical

Generic Name: bcg

Brand Name: Tice BCG Live, Tice BCG Vaccine, Theracys 3, TheraCys, BCG vaccine, Tice BCG

Synonyms: BCG intravesical, BCG (Intravesical)