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Boniva (Ibandronate Injection) and Renal dysfunction

Result of checking the interaction of drug Boniva (Ibandronate Injection) and disease Renal dysfunction for safety when used together.

Check result:

Boniva (Ibandronate Injection) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ibandronate is not recommended for use in patients with severe renal impairment (creatinine clearance less than 30 mL/min). The portion of ibandronate that is not removed from the circulation via bone absorption is eliminated unchanged by the kidney (approximately 50% to 60% of the absorbed dose). Unabsorbed ibandronate is eliminated unchanged in the feces. Renal clearance of ibandronate in patients with various degrees of renal impairment is linearly related to creatinine clearance (CrCl). Treatment with intravenous bisphosphonates has been associated with renal toxicity manifested as deterioration in renal function and acute renal failure. Obtain serum creatinine prior to each ibandronate sodium injection. After ibandronate sodium injection, assess renal function, as clinically appropriate, in patients with concomitant diseases or taking medications that have the potential for adverse effects on the kidney.

Boniva (Ibandronate Injection)

Generic Name: ibandronate

Brand Name: Boniva, Bondronat

Synonyms: Boniva

What is Boniva (Ibandronate Injection)?