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Buphenyl (Sodium Phenylbutyrate Tablets) and Liver disease

Result of checking the interaction of drug Buphenyl (Sodium Phenylbutyrate Tablets) and disease Liver disease for safety when used together.

Check result:
Buphenyl (Sodium Phenylbutyrate Tablets) <> Liver disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sodium phenylbutyrate is primarily metabolized in the liver and kidney. Therapy with sodium phenylbutyrate should be administered cautiously in patients with liver disease. Monitoring plasma levels of ammonia, arginine, branched-chain amino acids and serum proteins to maintain within normal limits and glutamine to less than 1000 mcmol/L is recommended.

References:
  • "Product Information. Buphenyl (sodium phenylbutyrate)." Horizon Pharma USA Inc, Northbrook, IL.
Buphenyl (Sodium Phenylbutyrate Tablets)

Generic Name: sodium phenylbutyrate

Brand Name: Buphenyl

Synonyms: Buphenyl

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