Drug search by name

Buphenyl (Sodium Phenylbutyrate Tablets) and Neurotoxicity

Result of checking the interaction of drug Buphenyl (Sodium Phenylbutyrate Tablets) and disease Neurotoxicity for safety when used together.

Check result:

Buphenyl (Sodium Phenylbutyrate Tablets) <> Neurotoxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sodium phenylbutyrate is a pro-drug and is rapidly metabolized to the active, phenylacetate. Neurotoxicity, including exacerbation of a preexisting neuropathy, has been reported with the use of intravenous phenylacetate. The acute onset and reversibility when the phenylacetate infusion was discontinued suggested a drug effect. Care should be exercised when prescribing sodium phenylbutyrate to patients at risk for neurotoxicity.

Buphenyl (Sodium Phenylbutyrate Tablets)

Generic Name: sodium phenylbutyrate

Brand Name: Buphenyl

Synonyms: Buphenyl

What is Buphenyl (Sodium Phenylbutyrate Tablets)?