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Butalbital, Aspirin, Caffeine, and Codeine and Cardiotoxicity

Generic Name: aspirin / butalbital / caffeine / codeine
Dosage Forms: n.a.
Other Brand Names: Ascomp with Codeine , Fiorinal with Codeine , Fiortal with Codeine, Ascomp-Codeine, Fiorinal/Codeine #3

Result of checking the interaction of drug Butalbital, Aspirin, Caffeine, and Codeine and disease Cardiotoxicity for safety when used together.

Check result:

Butalbital, Aspirin, Caffeine, and Codeine <> Cardiotoxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Like other methylxanthines, caffeine at high dosages may be associated with positive inotropic and chronotropic effects on the heart. Caffeine may also produce an increase in systemic vascular resistance, resulting in elevation of blood pressure. Therapy with products containing caffeine should be administered cautiously in patients with severe cardiac disease, hypertension, hyperthyroidism, or acute myocardial injury. Some clinicians recommend avoiding caffeine in patients with symptomatic cardiac arrhythmias and/or palpitations and during the first several days to weeks after an acute myocardial infarction.

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