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Cabozantinib S-malate and Hepatic impairment

Result of checking the interaction of drug Cabozantinib S-malate and disease Hepatic impairment for safety when used together.

Check result:
Cabozantinib S-malate <> Hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Increased exposure to cabozantinib has been observed in patients with mild to moderate hepatic impairment. It is recommended to reduce the cabozantinib dose in patients with mild or moderate hepatic impairment. The use of cabozantinib is not recommended in patients with severe hepatic impairment. It is recommended to monitor liver function and urine bilirubin tests periodically during therapy.

Cabozantinib S-malate

Generic Name: cabozantinib

Brand Name: Cabometyx, Cometriq

Synonyms: Cabozantinib

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