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Cidofovir Intravenous and Neutropenia

Result of checking the interaction of drug Cidofovir Intravenous and disease Neutropenia for safety when used together.

Check result:

Cidofovir Intravenous <> Neutropenia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cidofovir may cause neutropenia (20% in clinical trials). Therapy with cidofovir should be administered cautiously in patients with preexisting neutropenia or those receiving concomitant drugs with myelosuppressive effects. With some drugs (e.g., zidovudine or AZT), a temporary interruption of therapy or a reduction in dosage may be necessary on days of cidofovir administration. Close monitoring of neutrophil count is recommended during therapy with cidofovir. Some patients may be candidates for granulocyte colony stimulating factor.

References:

Lalezari JP, Drew WL, Glutzer E, James C, Miner D, Flaherty J, Fisher PE, Cundy K, Hannigan J, Martin JC, et al "(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue." J Infect Dis 171 (1995): 788-96
"Product Information. Vistide (cidofovir)." Gilead Sciences, Foster City, CA.

Cidofovir Intravenous

Generic Name: cidofovir

Brand Name: Vistide

Synonyms: Cidofovir

What is Cidofovir Intravenous?