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Clonazepam Tablets and Renal/liver disease

Generic Name: clonazepam
Dosage Forms: n.a.
Other Brand Names: Klonopin , Klonopin Wafer

Result of checking the interaction of drug Clonazepam Tablets and disease Renal/liver disease for safety when used together.

Check result:

Clonazepam Tablets <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of clonazepam is considered by the manufacturer to be contraindicated in patients with clinical or biochemical evidence of significant liver disease. Clonazepam is primarily metabolized by the liver, and the metabolites are eliminated by the kidney. Due to the possibility of excess accumulation of metabolites and the unknown effects of such accumulation, therapy with clonazepam should also be administered cautiously in patients with renal impairment.

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