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Corzide 40/5 and Renal dysfunction

Result of checking the interaction of drug Corzide 40/5 and disease Renal dysfunction for safety when used together.

Check result:

Corzide 40/5 <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Nadolol is primarily eliminated by the kidney. Patients with renal impairment may be at greater risk for adverse effects from nadolol due to decreased drug clearance. Therapy with nadolol should be administered cautiously in patients with renal impairment. Dosage adjustments (i.e. prolongation of dosing interval) are recommended for patients with moderate to severe renal dysfunction (CrCl <= 50 mL/min).

References:

Herrera J, Vukovich RA, Griffith DL "Elimination of nadolol by patients with renal impairment." Br J Clin Pharmacol 7 (1979): s227-31
"Product Information. Corgard (nadolol)." Bristol-Myers Squibb, Princeton, NJ.

Corzide 40/5

Generic Name: bendroflumethiazide / nadolol

Brand Name: Corzide 40/5, Corzide 80/5, Corzide

Synonyms: n.a.

What is Corzide 40/5?