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Cosyntropin and Fluid retention

Result of checking the interaction of drug Cosyntropin and disease Fluid retention for safety when used together.

Check result:
Cosyntropin <> Fluid retention
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Adrenocorticotropic agents may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Therapy with these agents, particularly if intended for longer than brief periods, should be administered cautiously in patients with preexisting fluid retention or conditions that may be aggravated by these effects. Dietary sodium restriction and potassium supplementation may be advisable. The manufacturers consider the use of adrenocorticotropic agents to be contraindicated in patients with congestive heart failure or uncontrolled hypertension.

References:
  • "Product Information. Acthar (corticotropin)." Rhone-Poulenc Rorer, Collegeville, PA.
  • "Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.
  • "Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.
Cosyntropin

Generic Name: cosyntropin

Brand Name: Cortrosyn

Synonyms: n.a.

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