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Cosyntropin and Infections

Result of checking the interaction of drug Cosyntropin and disease Infections for safety when used together.

Check result:

Cosyntropin <> Infections

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The immunosuppressant and anti-inflammatory effects of adrenocorticotropic agents, particularly in higher dosages, may decrease host resistance to infectious agents, decrease the ability to localize infections, and mask the symptoms of infection. Secondary infections may be more likely to develop. In general, adrenocorticotropic agents should not be used in patients with active infections, especially systemic fungal infections, unless they are medically necessary and effective antimicrobial therapy or other appropriate treatment has been instituted. For patients who have received prolonged adrenocorticotropic therapy who develop a severe or life-threatening infection, supplemental doses of rapid-acting corticosteroids may be required, since these patients may have hypothalamic-pituitary insufficiency.

References:

"Product Information. Acthar (corticotropin)." Rhone-Poulenc Rorer, Collegeville, PA.
"Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.
"Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.

Cosyntropin

Generic Name: cosyntropin

Brand Name: Cortrosyn

Synonyms: n.a.

What is Cosyntropin?