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Cromolyn Inhalation, oral/nebulization and Renal/liver disease

Result of checking the interaction of drug Cromolyn Inhalation, oral/nebulization and disease Renal/liver disease for safety when used together.

Check result:

Cromolyn Inhalation, oral/nebulization <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Systemically absorbed cromolyn is eliminated almost equally by renal and biliary routes. Although less than 1% of an orally ingested dose and approximately 8% of an orally inhaled dose is systemically available, the manufacturers recommend that a dosage reduction be considered in patients with impaired renal or hepatic function.

References:

Fuller RW, Collier JG "The pharmacokinetic assessment of sodium cromoglycate." J Pharm Pharmacol 35 (1983): 289-92
"Product Information. Gastrocrom (cromolyn)." Rhone-Poulenc Rorer, Collegeville, PA.
Neale MG, Brown K, Hodder RW, Auty RM "The pharmacokinetics of sodium cromoglycate in man after intravenous and inhalation administration." Br J Clin Pharmacol 22 (1986): 373-82
Richards R, Dickson CR, Renwick AG, Lewis RA, Holgate ST "Absorption and disposition kinetics of cromolyn sodium and the influence of inhalation technique." J Pharmacol Exp Ther 241 (1987): 1028-32
"Product Information. Intal (cromolyn)." Rhone-Poulenc Rorer, Collegeville, PA.
Rosenberg JL, Edlow D, Sneider R "Liver disease and vasculitis in a patient taking cromolyn." Arch Intern Med 138 (1978): 989-91
Walker SR, Evans ME, Richards AJ, Paterson JW "The fate of [14C]disodium cromoglycate in man." J Pharm Pharmacol 24 (1972): 525-31

Cromolyn Inhalation, oral/nebulization

Generic Name: cromolyn

Brand Name: Gastrocrom

Synonyms: Cromolyn sodium, Cromolyn (Oral Inhalation)

What is Cromolyn Inhalation, oral/nebulization?