Cylert and Renal dysfunction
Result of checking the interaction of drug Cylert and disease Renal dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Pemoline is primarily eliminated by the kidney. The plasma clearance of pemoline may be decreased and the half-life prolonged in patients with renal impairment. Therapy with pemoline should be administered cautiously in patients with significantly impaired renal function. Dosage adjustments may be necessary.
- "Product Information. Cylert (pemoline)." Abbott Pharmaceutical, Abbott Park, IL.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Overall CNS stimulants should be administered with caution in patients with significantly impaired renal function as the reduction in the rate of elimination may alter the therapeutic response. The dosage should be adjusted accordingly.
- "Product Information. Provigil (modafinil)." Cephalon, Inc, West Chester, PA.